CIHR boosts health research in London

Scientists at The University of Western Ontario and the Lawson Health Research Institute jointly received more than $13-million from the Canadian Institutes of Health Research (CIHR) this week in support of an array of medical research.

The announcement included operating funding for a total of 28 London projects ranging from research into osteoarthritis and kidney damage to prenatal health and obesity.

London researchers continue to do very well in a highly competitive national funding environment. The funding success rate for applications submitted from London scientists to CIHR was 27 per cent while the national average was 17 per cent.

Western researchers receiving funding include investigators from the Schulich School of Medicine & Dentistry, Robarts Research Institute, Lawson Health Research Institute and the Richard Ivey School of Business.

The successful projects include:

  • Frank Beier received $713,501 (five years) for the project, “TGFalpha/EGFR signaling in osteoarthritis”
  • Nica Borradaile received $91,439 (one year) for “Roles of elongation factor 1A-1 in apolipoprotein B metabolism and the pathogenesis of nonalcoholic fatty liver disease”
  • Peter Chidiac received $539,515 (five years) for the project, “Role of RGS2 in the response of cells to stress”
  • Lina Dagnino received $703,280 (five years) for the project, “Integrin-linked kinase in epidermal stem cells”
  • Neil Duggal received $325,808 (four years) for the project, “Metabolic and functional correlates in spinal cord compression measured by Magnetic Resonance Imaging”
  • Stefan Everling received $854,155 (five years) for the project “Role of frontal cortical projection to the superior colliculus in saccade suppression and task switching in primates”
  • Stephen Ferguson received $758,070 (five years) for the project “Regulation of Vascular G Protein-coupled Receptor Signal Transduction”
  • Amit Garg received funding for four projects, including: 
    • $99,210 (two years) for “Acute kidney injury from antiviral drugs for herpes infections: A population-based study of older adults”
    • $139,828 (two years) for “Electrolyte Disorders from Common Medications: Risk and Mitigation”
    • $119,920 (two years) for “Preoperative Medications and Acute Kidney Injury: A VISION sub-study”
    • $59,951 (one year) for “Filtering Medline for Renal Information: Renal Sub-Filters”
  • Lakshman Gunaratnam received $100,000 (one year) for “Exploiting KIM-1 signalling to ameliorate acute kidney injury through clearance of apoptotic cells”
  • Daniel Hardy received $364,704 (three years) for the project, “Molecular mechanisms underlying the in utero origins of hypercholesterolemia”
  • Robert Hegele received $599,814 (five years) for the project, “Genetic architecture of cardiometabolic risk in families and communities”
  • David Heinrichs received $702,770 (five years) for the project, “Role of iron and heme binding proteins in pathogenesis of Staphlococcus aureus”
  • David Holdsworth received $752,848 (five years) for the project, “Single-plane dynamic radiography for quantification of bone and joint motion”
  • Anthony Jevnikar received $609,640 (five years) for the project, “Regulation of renal tubular epithelial cell injury to promote kidney allograft survival”
  • John MacDonald received $1,048,740 (five years) for his project “NMDA Receptors, Metaplasticity and Schizophrenia”
  • Mellissa Mann received $833,106 (five years) for the project, “Molecular analysis of genomic imprint maintenance during embryogenesis”
  • Ravi Menon received $912,635 (five years) for his project “Ultra high field MRI measurements of tissue magnetic susceptibility in Multiple Sclerosis”
  • Joseph Mymryk received $807,400 (five years) for the project, “Molecular genetic analysis of adenovirus E1A function”
  • Giles Santyr received $367,905 (three years) for his project “Functional and Metabolic Magnetic Resonance Imaging of Lung Inflammation”
  • Samuel Siu received $405,600 (three years) for the project, “Pregnancy and Subsequent Cardiovascular Risk in Women with Heart Disease”
  • Rommel Tirona received $584,056 (four years) for the project, “Role of Skeletal Muscle Drug Transporters in Statin-Induced Myopathy”
  • Ruud Veldhuizen received $100,000 (one year) for “The effects of mechanical ventilation on the biophysical properties of pulmonary surfactant”
  • Hao Wang received $316,529 (three years) for the project, “Mechanisms of Soluable CD83 in Prevention of Antibody Mediated Rejection”
  • Kaiping Yang received $566,323 (four years) for the project, “Early-life origins of visceral adiposity”
  • Gregory Zaric received $173,829 (three years) for his project “Economic evaluation of tests to reveal the source of cancers of unknown primary”