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Robarts Research Institute

Developing low-cost microscopes for early malaria detection

Western professor Ian Cunningham is working to help people in Uganda have better access to life-saving testing and early diagnosis of malaria.

Ian Cunningham

Cunningham, a Schulich Medicine & Dentistry professor and scientist at Robarts Research Institute, is the research mentor on a project to develop a low-cost digital light microscope for remote diagnosis of malaria in poor populations. With funding from Academics Without Borders (AWB), Cunningham works closely with William Wasswa, project lead and a professor at Mbarara University of Science & Technology in Uganda. “Treatments for malaria are only effective if you can diagnose quickly in rural environments so they can be started on a treatment regime quickly,” said Cunningham. “The current system of sending a sample to labs in big cities for diagnosis is a barrier to that. My colleague proposed developing a low-cost microscope that can be brought to these locations.” The project aims to build such microscope for under $500. Currently, the cost of a microscope lens alone is around $2,000, Cunningham said. “This would be a game-changing difference and can have a very high impact.” Cunningham and Wasswa’s project proposal was successfully selected for funding through the AWB’s Strengthening Engineering Education and Research (SEER) program. “The goal of the SEER program is for mentors from primarily Canadian institutions to work with faculty in Uganda, who haven’t completed their PhDs or who don’t have research backgrounds. We’re called supervisors, but we’re really collaborators,” said Cunningham, adding the idea for their project was proposed by Wasswa as a way to address malaria, a leading cause of death among young people in Uganda. Their project builds on previous work done in this area in recent years. In addition to being smaller and less expensive, to be effective in many rural areas, microscopes must also be battery operated, able to withstand impact caused by bouncing around on hard roads, and easy to use. “We have to build the prototype, evaluate it, then do rural testing. Within the year, we will also have an external research proposal written and submitted,” Cunningham said. “The end goal, ultimately, is that the slides will be digitally imaged locally and sent back to the lab digitally, but our first objective is to make sure pathologists are getting the right images to diagnose.” Cunningham said he is looking forward to continuing this research and the potential for the group to make this scientific contribution. “We’re really invested in this project succeeding. I got involved in the program because I’ve been distressed for a few years now about the politics in this world. Public education in some countries is fabulous and some countries have fabulous private education, but you see the frailty of democracy in so many places. We need to have smart people who like to talk to keep a democracy moving. I’m a scientist and can work with local educators. Science education is where I can help.”

Michael J. Fox to speak in London

Actor Michael J. Fox will be the guest speaker at the Leaders in Innovation Dinner which celebrates the 25th anniversary of Robarts Research Institute at Western’s Schulich School of Medicine & Dentistry.

WORLDiscoveries expands into China

WORLDiscoveries is open for business in China. The organization, a partnership between The University of Western Ontario, Robarts Research Institute and Lawson Health Research Institute, will open an office in the Jiangsu province in southern China in November.

Stem cell scientist awarded Taylor Prize

Dr. Rudolf Jaenisch, a founding member of the Whitehead Institute for Biomedical Research and professor of biology at the Massachusetts Institute of Technology, has been named this year’s recipient of the J. Allyn Taylor International Prize in Medicine.

CIHR boosts health research in London

Scientists at The University of Western Ontario and the Lawson
Health Research Institute jointly received more than $13-million
from the Canadian Institutes of Health Research (CIHR) this week in
support of an array of medical research.